Everee #3 - Peri-menopause Support
What It Does
Everee Women™ #3 Peri-menopause Support is specifically designed for women going through peri-menopause. With Ovitage® Collagen boasting an amino acid balance substantially higher in cystine, tyrosine and glutamic acid. Everee Women™ #3 is your protein powerhouse for sustained support right through menopause.
Improve gut health and the gut-skin axis: Healthy gut = healthy skin.
Improve the gut microbiome
Reduce "leaky gut", reduce bloating, and improve bowel health.
Reduce hair fall and improve hair quality.
Smoother, more hydrated skin
Can help improve brain fog and mood
Why Choose Everee Women™ #3?
- Comprehensive Formula: Scientifically extracted and formulated with biochemistry specifically for perimenopausal women, effectively addressing multiple menopause symptoms while promoting overall well-being.
- High-Quality Ingredients: Entirely made from New Zealand sources and formulated by New Zealand’s leading protein extraction scientists to ensure maximum bioavailability and effectiveness.
- Easy to Incorporate: Designed for busy lifestyles with a simple, ‘any way you want to take it’ approach that can be easily incorporated into your diet with no artificial additives or preservatives
| Amino Acid | Profile per 100gms | Benefit |
| Cystine | 1.79 |
Builds skin structural proteins to boost skin firmness and reduce leaky gut. Fights skin stress, redness and inflammation. |
| Tyrosine | 1.14 | Reduces stress and improves mood by helping the body produce dopamine and epinephrine. |
| Glutamic Acid | 13.03 | Improves cognitive performance and memory by increasing the neurotransmitter glutamate. |
| Livaux® Gold Kiwifruit extract | 8.0 | Promotes a healthy gut microbiome by boosting production of the microbe F. prausnitzii |
Real Science & Real Results - How it does it
Everee 3 contains Ovitage® the world’s most complete collagen derived from whole ovine skin and produced using a proprietary process that isolates all of the skin's important components, including structural proteins well beyond the collagen I and III common in traditional collagen products. This functionality is boosted by Livaux®, a clinically proven prebiotic extracted from gold kiwifruit. The result is a protein powder rich in specific amino acids ideally suited to boost the body’s ability to deal with the challenges of perimenopause, from gut health to hair loss, skin health and brain fog.
Gut health and the gut-skin axis
Establishing a healthy gut microbiome is essential for gut health, and the connection to skin health through the gut-skin axis is well established. The Livaux® in Everee 3 has been shown in clinical studies to promote the gut microbe F. prausnitzii (1), thereby reducing gastrointestinal disorders and improve anti inflammatory activity in the gut.
Dropping oestrogen levels reduce the body's ability to produce specific collagens, in particular in the intestinal membranes that may weaken as a result, leading to leaky gut. Boosting the body's ability to make the specific membrane proteins that build this epidermal structure helps combat this symptom of menopause. High cystine proteins have been shown to boost production of membrane proteins collagen IV and collagen VII (2) and the Ovitage® in Everee 3 has a substantially higher cystine content than traditional collagens.
Skin structure and hair health.
Collagen IV is the junctional protein responsible for joining the layers of the skin together and acting in each hair follicle to anchor hair in the head. As a whole skin extract, the Ovitage® in Everee 3 contains this important collagen type. Cystine rich proteins have been shown to increase collagen IV production in the skin and in the hair follicle and so improve skin firmness as well as follicle health to increase hair anchoring and reduce hair loss (3) and the Ovitage® in Everee 3 has substantially greater amounts of cystine than any other collagen or common dietary protein sources such as whey or soy. In addition, collagens, such as Ovitage® have been clinically proven to improve skin hydration (4).
Skin Inflammation
Skin stress during menopause arises from hormonal changes as well as oxidative stress from diet and environmental factors. This leads to skin inflammation and redness. High cystine proteins have been shown to significantly boost the body's production of taurine and glutathione (5). Taurine produced by the body is key to anti inflammatory activity through the taurine chloramine pathway (6). The Ovitage® in Everee 3 boosts this pathway, increasing the ability of the body to fight skin inflammation. Glutathione is known as an important antioxidant produced within skin cells to combat oxidative stress (7). Glutathione production requires cystine and boosting this pathway with high cystine protein specifically combats skin oxidative stress.
Cognitive performance
Glutamic acid is a form of glutamate, the most abundant transmitter in the nervous system and essential for healthy brain function and cognitive performance (8, 9). The impact of hormonal changes on this essential neurotransmitter have been reported in menopausal studies and good levels of glutamic acid from protein help maintain the appropriate balance of glutamate to boost brain function cognition and GABA for calming and anxiety relief (10).
Stress and mood
Studies directly show that increasing tyrosine through short term or long term protein ingestion raises brain tyrosine levels and boosts dopamine (and other catecholamine) production, specifically targeted at actively firing neurons (11). With substantially higher tyrosine than traditional collagen, the Ovitage® in Everee 3 provides the key building blocks for dopamine production and so for stress and mood control.
Dosage
Recommended daily dose of Everee 3 is 7.5g. Traditional collagens are established as effective in the range 2.5-15g (12) in studies on women experiencing perimenopause. The multiplying impact of the high cystine component of Everee 3 is to stimulate greater protein synthesis (2), providing effectiveness at the lower dosage range compared to conventional collagen. Each dose contains 600mg of Livaux®, the recommended dose for prebiotic function.
References
1. P Blatchford, H Stoklosinski, S Eady, A Wallace, C Butts, R Gearry, G Gibson and J Ansell, Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. Journal of Nutritional Science (2017), vol. 6, e52, pp 1-10.
2. L Tang, J Ollague Sierra, R Kelly, R S Kirsner, J Li, Wool-derived keratin stimulates human keratinocyte migration and types IV and VII collagen expression, Experimental Dermatology, 21, 5, 2012, DOI: 10.1111/j.1600-0625.2012.01505.x
3. Roddick-Lanzilotta A., Kelly R. and Sapsford P., A hold on hair. Keratin blend anchors follicles and prevents pollution induced hair fall. Cosmetics and Toiletries, 134, 9, 24-36, 2019.
4. Bolke L, Schlippe G, Gerß J, Voss W. A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients. 2019 Oct 17;11(10):2494. doi: 10.3390/nu11102494. PMID: 31627309; PMCID: PMC6835901.
5. Wolber F., McGrath M., Jackson F., Wylie K. and Broomfield A., Cysteic Acid in Dietary Keratin is Metabolized to Glutathione and Liver Taurine in a Rat Model of Human Digestion, Nutrients (2016) 8 (2): 104.
6. Marcinkiewicz J, Kontny E. Taurine and inflammatory diseases. Amino Acids. 2014 Jan;46(1):7-20. doi: 10.1007/s00726-012-1361-4. Epub 2012 Jul 19. PMID: 22810731; PMCID: PMC3894431.
7. McPherson R. and Hardy G., Clinical and nutritional benefits of cysteine-enriched protein supplements, Current Opinion in Clinical Nutrition and Metabolic Care (2011), 14:562–568.
8. Zhou Y, Danbolt NC. Glutamate as a neurotransmitter in the healthy brain. J Neural Transm (Vienna). 2014 Aug;121(8):799-817. doi: 10.1007/s00702-014-1180-8. Epub 2014 Mar 1. PMID: 24578174; PMCID: PMC4133642
9. Alexander S, Glutamate, Encyclopaedia of Neuroscience, 2009, 885-594. doi.org/10.1016/B978-008045046-9.00682-3.
10. Braden BB, Kingston ML, Koenig EN, Lavery CN, Tsang CW, Bimonte-Nelson HA. The GABAA antagonist bicuculline attenuates progesterone-induced memory impairments in middle-aged ovariectomized rats. Front Aging Neurosci. 2015 Aug 14;7:149. doi: 10.3389/fnagi.2015.00149. PMID: 26321945; PMCID: PMC4536389.
11. Fernstrom JD, Fernstrom MH. Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain. J Nutr. 2007 Jun;137(6 Suppl 1):1539S-1547S; discussion 1548S. doi: 10.1093/jn/137.6.1539S. PMID: 17513421.
12. Jendricke P, Centner C, Zdzieblik D, Gollhofer A, König D. Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial. Nutrients. 2019 Apr 20;11(4):892. doi: 10.3390/nu11040892. PMID: 31010031; PMCID: PMC6521629.
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