Everee #5 - Active Aging Support

What it does

Everee Women™ #5 Active Aging Support is designed to help women experience the beauty and richness that can accompany this stage of life. Featuring Ovitage® Collagen and boosted by the concentrated benefits of New Zealand olive leaf extract and nutrient dense sheep milk, this protein powder is rich in amino acids and polyphenols ideally suited to support the needs of healthy ageing.  

Muscle Maintenance: Branched chain amino acids including cystine and leucine help build lean muscle mass. 

Bone Strength: Sheep milk helps improve bone density and reduce the risk of osteoporosis. 

Joint Support: High cystine proteins in Ovitage® helps boost production of structural proteins important for joint mobility and fighting inflammation.   

Mental Clarity: Glutamic acid and tyrosine support healthy brain function and cognitive performance.  

Heart Health: Oleuropein from New Zealand grown olive leaves helps provide cardioprotection and reduce the effect of cholesterol

Why Choose Everee Women™ #5

Embrace this chapter of life with vitality and confidence. Everee Women™ #5 Active Aging is more than a supplement – it's your partner in maintaining an active, fulfilling lifestyle as you age. Stay sharp and keep living well.

• Comprehensive Formula: Addresses multiple concerns specific to mature adults in one convenient supplement.
• Quality Assured: Each batch is rigorously tested for purity and potency.
• Easy to Incorporate: Designed for convenient daily use, fitting seamlessly into your routine.
• Science-Backed: Formulated based on the latest research in healthy aging

Real Science & Real Results - How It Does It

Everee 5 contains Ovitage® the world’s most complete collagen derived from whole ovine skin and produced using a proprietary process that isolates all of the skin's important components, including structural proteins well beyond the collagen I and III common in traditional collagen products. This functionality is boosted by nutrient dense sheep milk and the concentrated benefits of New Zealand olive leaf extract. The result is a protein powder rich in the amino acids and polyphenols ideally suited to providing support for healthy ageing and to address the needs of maintaining lean body mass, maintaining mental clarity and hearth health and protecting against inflammation. 

How it works

Muscle Maintenance and Fighting Sarcopenia

Muscle mass is harder to retain as we age. Branched chain amino acids such as isoleucine, leucine and valine are essential for building lean body mass (1) with leucine of particular importance for ageing women (2). Due to use of the unique Ovitage® protein, and complemented with New Zealand sheep milk, Everee Women™ #5 provides substantially more of these crucial amino acids than traditional collagen or dairy proteins and, as a result, assists in retaining muscle mass. The high cystine proteins in Ovitage® have demonstrated the ability to contribute further to the maintenance of lean body mass with studies showing substantial increase in lean body mass as a result of a high cystine protein diet, compared to a dairy protein control (3). Clinical studies of sheep milk protein have also shown increased branched chain amino acid concentrations (including leucine, valine and isoleucine) in women consuming sheep milk (14), making the combination well suited to support muscle maintenance and building lean body mass for healthy ageing.  

Bone Strength, Joint Support, Inflammation

The sheep milk in Everee Women™ #5 is 70% higher in calcium than cow’s milk, providing a superior source for improving bone density and reducing the risk of osteoporosis. In addition, the high cystine proteins in Ovitage® have been shown to stimulate production of structural proteins, including junctional collagens, that are important for joint mobility support in ageing tissue (4). High cystine proteins have also been shown to significantly boost the body's production of taurine and glutathione (5). Taurine produced by the body is key to anti-inflammatory activity through the taurine chloramine pathway (6). Due to high cystine content, Everee Women™ #5 boosts this pathway, increasing the ability of the body to fight chronic inflammation. Glutathione is known as an important antioxidant produced within cells to combat oxidative stress and acute or chronic inflammation (7). Cystine enriched proteins such as Ovitage® boost glutathione production resulting in recognised benefits from combatting inflammation and oxidative stress (7). 

Mental Clarity

Glutamic acid is a form of glutamate, the most abundant transmitter in the nervous system and essential for healthy brain function and cognitive performance (8, 9).  This is supported by the dopamine precursor tyrosine, shown as essential for cognition in particular when under stress or cognitive demand, as occurs during ageing (10). The Ovitage® in Everee Women™ #5 contains twice as much of these important amino acids compared to conventional collagen and so assists cognitive performance during ageing.  

Heart Health

Oleuropein is a polyphenolic bioactive compound richer in New Zealand grown olive leaves than conventional olive oil. Oleuropein has been well established as providing cardioprotective effects, and recent clinical studies have demonstrated the mechanism of preventing myocardial injury (11) is via enhanced production of nitric oxide and its associated vasodilation effect (12).  Oleuropein's antioxidant activity further helps prevent the impact of LDL cholesterol on the body by preventing it’s passage into cells, a key step in reducing the development of atherosclerosis (hardening of the arteries) (12).

Dosage

Recommended daily dose of Everee Women™ #5 Active Aging Support is 7.5g. Traditionally, collagens and protein supplements are established as effective in the range 2.5-15g (13) with 15g effective for improving lean body mass in women. The multiplying effect of the high cystine component of Ovitage® in Everee Women™ #5 is to stimulate greater protein synthesis (4), providing effectiveness at the lower dosage range.

References

1. Dudgeon WD, Kelley EP, Scheett TP. In a single-blind, matched group design: branched-chain amino acid supplementation and resistance training maintains lean body mass during a caloric restricted diet. J Int Soc Sports Nutr. 2016 Jan 5;13:1. doi: 10.1186/s12970-015-0112-9. PMID: 26733764; PMCID: PMC4700774.
2. Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T. Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2015 Sep 1;16(9):740-7. doi: 10.1016/j.jamda.2015.05.021. Epub 2015 Jul 10. PMID: 26170041.
3. Crum EM, McLeay YD, Barnes MJ, Stannard SR. The effect of chronic soluble keratin supplementation in physically active individuals on body composition, blood parameters and cycling performance. J Int Soc Sports Nutr. 2018 Sep 27;15(1):47. doi: 10.1186/s12970-018-0251-x. PMID: 30261892; PMCID: PMC6161438.
4. L Tang, J Ollague Sierra, R Kelly, R S Kirsner, J Li, Wool-derived keratin stimulates human keratinocyte migration and types IV and VII collagen expression, Experimental Dermatology, 21, 5, 2012, DOI: 10.1111/j.1600-0625.2012.01505.x
5. Wolber F., McGrath M., Jackson F., Wylie K. and Broomfield A., Cysteic Acid in Dietary Keratin is Metabolized to Glutathione and Liver Taurine in a Rat Model of Human Digestion, Nutrients (2016) 8 (2): 104.
6. Marcinkiewicz J, Kontny E. Taurine and inflammatory diseases. Amino Acids. 2014 Jan;46(1):7-20. doi: 10.1007/s00726-012-1361-4. Epub 2012 Jul 19. PMID: 22810731; PMCID: PMC3894431.
7. McPherson R. and Hardy G., Clinical and nutritional benefits of cysteine-enriched protein supplements, Current Opinion in Clinical Nutrition and Metabolic Care (2011), 14:562–568.
8. Zhou Y, Danbolt NC. Glutamate as a neurotransmitter in the healthy brain. J Neural Transm (Vienna). 2014 Aug;121(8):799-817. doi: 10.1007/s00702-014-1180-8. Epub 2014 Mar 1. PMID: 24578174; PMCID: PMC4133642
9. Alexander S, Glutamate, Encyclopaedia of Neuroscience, 2009, 885-594. doi.org/10.1016/B978-008045046-9.00682-3.
10. Jongkees BJ, Hommel B, Kühn S, Colzato LS. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. J Psychiatr Res. 2015 Nov;70:50-7. doi: 10.1016/j.jpsychires.2015.08.014. Epub 2015 Aug 25. PMID: 26424423.
11. Manna, C.; Migliardi, V.; Golino, P.; Scognamiglio, A.; Galletti, P.; Chiariello, M.; Zappia, V. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. J. Nutr. Biochem., 2004, 15, 461-466.
12. Magrone, Thea & Spagnoletta, Anna & Salvatore, Rosaria & Magrone, Manrico & Dentamaro, Francesco & Russo, Matteo & Difonzo, Graziana & Summo, Carmine & Caponio, Francesco & Jirillo, Emilio. (2017). Olive Leaf Extracts Act as Modulators of the Human Immune Response. Endocrine, metabolic & immune disorders drug targets. 17.
13. Jendricke P, Centner C, Zdzieblik D, Gollhofer A, König D. Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial. Nutrients. 2019 Apr 20;11(4):892. doi: 10.3390/nu11040892. PMID: 31010031; PMCID: PMC6521629.
14. Milan Amber M. , Samuelsson Linda M. , Shrestha Aahana , Sharma Pankaja , Day Li , Cameron-Smith David. Circulating Branched Chain Amino Acid Concentrations Are Higher in Dairy-Avoiding Females Following an Equal Volume of Sheep Milk Relative to Cow Milk: A Randomized Controlled Trial, Frontiers in Nutrition, 7, 2020. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2020.553674